When to Pick the Nose: Out-of-Hospital and Emergency Department Intranasal Administration of Medications.
Annals of Emergency Medicine · 2017-03-30 · Other / unclear
Abstract
The intranasal route for medication administration is increasingly popular in the emergency department and out-of-hospital setting because such administration is simple and fast, and can be used for patients without intravenous access and in situations in which obtaining an intravenous line is difficult or time intensive (eg, for patients who are seizing or combative). Several small studies (mostly pediatric) have shown midazolam to be effective for procedural sedation, anxiolysis, and seizures. Intranasal fentanyl demonstrates both safety and efficacy for the management of acute pain. The intranasal route appears to be an effective alternative for naloxone in opioid overdose. The literature is less clear on roles for intranasal ketamine and dexmedetomidine.
Abstract © the authors or publisher, via PubMed. Reuse and removal
Tags
Analgesics · Intranasal administration · Anaesthetics · Sedatives & anxiolytics · Ketamine · Fentanyl · Midazolam · Antidotes · Naloxone
Related articles
- Safety and efficacy of intranasally administered medications in the emergency department and prehospital settings. (Am J Health Syst Pharm, 2015)
- What is the Evidence for Using Intranasal Medicine in the Prehospital Setting? A Systematic Review. (Prehosp Emerg Care, 2024)
- Stability of Drugs Stored in Helicopters for Use by Emergency Medical Services: A Prospective Observational Study. (Ann Emerg Med, 2022)
- Italian Intersociety Recommendations on pain management in the emergency setting (SIAARTI, SIMEU, SIS 118, AISD, SIARED, SICUT, IRC). (Minerva Anestesiol, 2015)
- Prehospital Use of Ketamine in Mountain Rescue: A Survey of Emergency Physicians of a Single-Center Alpine Helicopter-Based Emergency Service. (Wilderness Environ Med, 2020)
- Analgosedation in Pediatric Emergency Care: A Comprehensive Scoping Review. (Pharmaceuticals (Basel), 2024)