Assessing the clinical utilization of tranexamic acid by paramedics for patients with major trauma (ACUTE).
CJEM · 2021-01-04 · Observational study
Abstract
OBJECTIVES: This study aimed to characterize the clinical utilization of tranexamic acid (TXA) by paramedics in British Columbia (BC) for acute major trauma and to quantify the percentage of patients who received TXA among those who met the indications for administration. METHODS: A quality assurance review of eligible trauma patients across the province was performed using a convenience sample. Trauma patients between April 1, 2016 and March 31, 2017 with suspected or actual hemorrhage were selected if they met inclusion criteria (systolic blood pressure < 90 mm Hg ± heart rate > 120 beats per minute) and exclusion criteria (age < 16 years, injuries exclusively to the extremities). RESULTS: 35 of the 100 eligible patients assessed in this review received a dose of TXA from paramedics. All 35 of the patients received TXA within 180 min of injury regardless of their original location of injury in BC (mean: 50 min; range: 15-140 min). CONCLUSIONS: 35% of eligible patients identified in this study received TXA, which is an improvement over rates cited by previous Canadian literature. With further education opportunities for paramedics in BC and other EMS systems, there is potential to continue improving pre-hospital TXA administration rates.
Abstract © the authors or publisher, via PubMed. Reuse and removal
Tags
Haemostatics · Tranexamic acid · Paramedics & EMTs
Related articles
- Tranexamic acid in polish pre-hospital emergency medicine and the competencies of medical rescue teams (Disaster and Emergency Medicine Journal, 2022)
- Barriers and facilitators to the administration of prehospital tranexamic acid: a paramedic interview study using the theoretical domains framework. (Emerg Med J, 2022)
- Validation of the BATT score for prehospital risk stratification of traumatic haemorrhagic death: usefulness for tranexamic acid treatment criteria. (Scand J Trauma Resusc Emerg Med, 2021)
- Implementation of tranexamic acid for bleeding trauma patients: a longitudinal and cross-sectional study. (Emerg Med J, 2019)
- Ukraine Trauma Project: the feasibility of introducing advanced trauma-care skills to frontline emergency medical services responders. (BMJ Open, 2023)
- Prioritising time-critical injuries and interventions for trapped motor vehicle collision patients: a Delphi study. (Scand J Trauma Resusc Emerg Med, 2025)