[The end-tidal carbon dioxide as an early sign and predictor of the return of spontaneous circulation during out-of-hospital cardiac arrest. A systematic review.].
Revista espanola de salud publica · 2021-04-27 · Systematic review
Abstract
BACKGROUND: There is no clear evidence on the maximum level of end-tidal carbon dioxide (ETCO2) predictor of the return of spontaneous circulation (RSC) after an out-of-hospital cardiorespiratory arrest. The aims of this work was to synthesise and analyse the available evidence on the usefulness of monitoring values ETCO2 in an out-of-hospital cardiorespiratory arrest as an early sign and prognostic indicator of the RSC. METHODS: Systematic review, with narrative synthesis of the results, of primary studies published in English or Spanish was conducted in Medline, CINAHL, Web of Science, EMBASE, Proquest, Scopus, Cochrane, ÍnDICEs CSIC and CUIDEN of studies that analyse the usefulness of monitoring of the level of ETCO2 as a sign of the RSC after an out-of-hospital cardiorespiratory arrest. PRISMA declaration was followed. The risk of bias was assessed with the Newcastle-Ottawa Scale. RESULTS: 1,011 studies were found, eight of which fulfilled the inclusion criteria. The studies reported an association between the abrupt increase in ETCO2 and RSC to disagree on the predictive cut-off points (an increase than 10 mmHg and initial values or three minutes greater than 10 mmHg or 19 mmHg). The studies were of moderate to high methodological quality. CONCLUSIONS: ETCO2 values correlate with the RSC in adults with cardiorespiratory arrest and could predict non-survival, so they should be incorporated into advanced life support algorithms and Utstein-style reports.
Abstract © the authors or publisher, via PubMed. Reuse and removal
Tags
Capnography · Mortality & survival
Related articles
- Resuscitation From Out-of-Hospital Cardiac Arrest: When Is EtCO2 Reliably Associated With ROSC? (Circulation, 2026)
- Near-infrared spectroscopy, pupillometry and end-tidal CO2 as predictive factors of survival at hospital admission after out-of-hospital cardiac arrest. (Resusc Plus, 2026)
- Cerebral oxygen saturation in relation to end-tidal CO2 in cardiopulmonary resuscitation - Separate views of brain and body? (Resusc Plus, 2025)
- The peak end-tidal carbon dioxide concentration recorded during cardiopulmonary resuscitation as an indicator of survival: a nationwide cohort study of pediatric out-of-hospital cardiac arrests. (Resuscitation, 2025)
- End-Tidal Carbon Dioxide Measurement in Out-of-Hospital Cardiac Arrest as a Predictor of Return of Spontaneous Circulation: A Literature Review. (Dimens Crit Care Nurs, 2024)
- Temporal Trends in End-Tidal Capnography and Outcomes in Out-of-Hospital Cardiac Arrest: A Secondary Analysis of a Randomized Clinical Trial. (JAMA Netw Open, 2024)