Resuscitation for out-of-hospital cardiac arrest in Ireland 2012-2020: Modelling national temporal developments and survival predictors.
Resuscitation Plus · 2024-04-18 · Registry study
Abstract
AIM: To explore potential predictors of national out-of-hospital cardiac arrest (OHCA) survival, including health system developments and the COVID pandemic in Ireland. METHODS: National level OHCA registry data from 2012 through to 2020, relating to unwitnessed, and bystander witnessed OHCA were interrogated. Logistic regression models were built by including predictors through stepwise variable selection and enhancing the models by adding pairwise interactions that improved fit. Missing data sensitivity analyses were conducted using multiple imputation. RESULTS: The data included 18,177 cases. The final model included seventeen variables. Of these nine variables were involved in pairwise interactions. The COVID-19 period was associated with reduced survival (OR 0.61, 95%CI 0.43, 0.87), as were increasing age in years (OR 0.96, 95% CI 0.96, 0.97) and call response interval in minutes (OR 0.97, 95% CI 0.96, 0.99). Amiodarone administration (OR 3.91, 95% CI 2.80, 5.48), urban location (OR 1.40, 95% CI 1.12, 1.77), and chronological year over time (OR 1.14, 95% CI 1.08, 1.20) were associated with increased survival. CONCLUSIONS: National survival from OHCA has significantly increased incrementally over time in Ireland. The COVID-19 pandemic was associated with decreased survival even after accounting for potential disruption to key elements of bystander and EMS care. Further research is needed to understand and address the discrepancy between urban and rural OHCA survival. Information concerning pre-event patient health status and inpatient care process may yield important additional insights in future.
Abstract © the authors or publisher, via PubMed. Reuse and removal
Tags
Amiodarone · Cardiovascular drugs · COVID-19 pandemic · Mortality & survival · Rural & remote · Time intervals · Urban
Related articles
- Assessing Key Factors Influencing Successful Resuscitation Outcomes in Out-of-Hospital Cardiac Arrest (OHCA). (J Clin Med, 2024)
- Differences in Out-of-Hospital Cardiac Arrest Management and Outcomes across Urban, Suburban, and Rural Settings. (Prehosp Emerg Care, 2023)
- Association Between Urban-Rural Geographical Location and 30-Day Survival After Out-of-Hospital Cardiac Arrest. (J Am Coll Emerg Physicians Open, 2026)
- Regional disparities and temporal trends in pre-hospital management of out-of-hospital cardiac arrest in Thailand: a multi-center retrospective cohort study (2017-2023). (Resusc Plus, 2026)
- Urban-rural disparities in out-of-hospital cardiac arrest outcomes: a nationwide Hungarian study. (Resusc Plus, 2025)
- Timing is survival: modeling how earlier calls improve cardiac arrest outcomes. (Front Digit Health, 2025)