The first case of a Caucasian child with calmodulinopathy related to CALM2 N98S mutation.
Cardiology in the young · 2026-02-01 · Case report
Abstract
We report the first Caucasian patient with CALM2 p. Asn98Ser, a 2-year-old girl who survived out-of-hospital cardiac arrest after emotional stress. The initial rhythm was broad-complex tachycardia degenerating into ventricular fibrillation. Normal QT intervals and absent structural disease suggest a CPVT-like presentation, highlighting diagnostic and management challenges in calmodulinopathy.