Survival from cardiac arrest at a core temperature of 14.0 °C on hospital arrival caused by cold exposure hypothermia treated with extracorporeal cardiopulmonary resuscitation: a case report.
Resuscitation plus · 2026-02-11 · Case report
Abstract
BACKGROUND: Accidental hypothermia complicated by cardiac arrest remains a challenging clinical condition, in which extracorporeal cardiopulmonary resuscitation (ECPR) may provide favorable outcomes in selected patients (Ruttmann et al., 2007; Walpoth et al., 1990). CASE PRESENTATION: A 70-year-old woman was found collapsed on a street near her home and was in cardiac arrest when emergency medical services arrived. On hospital arrival, her rectal temperature was 14.0 °C, and serum potassium measured from arterial blood was 8.68 mmol/L. Accidental cold exposure hypothermia was presumed, and ECPR using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) was initiated (Ruttmann et al., 2007; Walpoth et al., 1990). Ventricular fibrillation occurred shortly after initiation of ECPR, and defibrillation was performed when the core body temperature reached 25.6 °C, resulting in return of spontaneous circulation and a favorable neurological outcome. The predicted survival probability according to the HOPE score was 40% (Pasquier et al., 2018). CONCLUSION: This case represents survival at one of the lowest core body temperatures reported on hospital arrival in an adult and highlights the established neuroprotective effects of profound hypothermia in accidental hypothermic cardiac arrest (Brown et al., 2012; McCullough and Arora, 2004; Gilbert et al., 2000; Sessler, 1997).