Novel Technologies for Identifying Treatment Assignment in a Prehospital Pediatric Emergency Care Clinical Trial.
Journal of the American College of Emergency Physicians Open · 2026-05-05 · Method & validation
Abstract
Clinical trials are essential for generating evidence-based knowledge to support clinical practice. In the prehospital setting, particular challenges exist in clinical trial design that have a large impact on the quality of the results, including the appropriate and systematic allocation of assigned treatment arm. The Pediatric Prehospital Airway Resuscitation Trial is a multicenter clinical trial evaluating different paramedic airway management strategies on critically ill and injured children in the prehospital setting. The trial assigns airway management strategy using odd-even day pseudo-randomization, which pragmatically balances the rigor of a statistical design that minimizes bias with the complexities of operationalizing a clinical trial in the prehospital setting. We describe the development of 2 technologies to aid in treatment assignment adherence during the trial: (1) a quick response code-linked web application, and (2) a self-contained portable reminder device. These technologies offer novel approaches to support treatment allocation in acute care clinical trials.
Abstract © the authors or publisher, via PubMed. Reuse and removal
Tags
Checklists & cognitive aids · Children · Paramedics & EMTs · Research methods & trial conduct
Related articles
- A mobile device app to reduce prehospital medication errors and time to drug preparation and delivery by emergency medical services during simulated pediatric cardiopulmonary resuscitation: study protocol of a multicenter, prospective, randomized controlled trial. (Trials, 2019)
- Community Acceptance of a Pediatric Prehospital Exception From Informed Consent Trial. (Acad Emerg Med, 2026)
- Critical Factors in Planning a Pediatric Prehospital Airway Trial. (Prehosp Emerg Care, 2022)
- Novel airway device Vie Scope in several pediatric airway scenario: A randomized simulation pilot trial. (Medicine (Baltimore), 2020)
- Comparison of Errors Using Two Length-Based Tape Systems for Prehospital Care in Children. (Prehosp Emerg Care, 2016)
- Randomized trial of endotracheal tube versus laryngeal mask airway in simulated prehospital pediatric arrest. (Pediatrics, 2008)