Does Simple Face Mask or Diffuser Mask Matter in the First Hour Treatment of Carbon Monoxide Intoxication? A Prospective Randomized Clinical Study
Eurasian Journal of Emergency Medicine · 2018-11-29 · Randomised trial
Abstract
Aim: In patients who do not have any indication for hyperbaric oxygen (O2) treatment, the main treatment to eliminate carbon monoxide (CO) is by giving O2 using a face mask. In the absence of a non-rebreathing face mask, a diffuser mask (DMG) or simple face mask (SMG) is an option that can be used for treatment. There are insufficient data about the acute efficacy of these masks. To study the ability of DMG and SMG in lowering carboxyhemoglobin (COHb) levels after the first hour of O2 treatment in patients with CO intoxication.Materials and Methods: This was a prospective randomized clinical study conducted in patients aged ≥16 years old who were diagnosed with CO intoxication. They were randomly given 15 L/min O2 (from hospital central O2 supplies) treatment with DMG (n=29) or SMG (n=52). Partial pressure of O2 (PaO2), carbon dioxide, and COHb levels and saturation of O2 were measured before and after 1 h of treatment.Results: A total of 81 (42 female and 39 male) patients with a mean age of 39.1±14.7 years were included in the study. There were no differences with regard to age, gender, body mass index, comorbidity, source of CO, initial symptoms, and initial COHb levels before treatment. After the first hour of treatment, DMG had lower mean COHb (mg/dL) levels (9.6±5.0 vs. 12.8±6.2, p=0.0203) and higher mean PaO2 levels (224.4±56.5 vs. 183.4±63.7, p=0.0046) than SMG.Conclusion: Diffuser mask (DMG) appears to be better than simple face mask (SMG) in the first hour of treatment of CO intoxication.
Abstract © the authors or publisher, via OpenAlex. Reuse and removal
Tags
Carbon monoxide · Other drugs · Oxygen · Poisoning & substance use
Related articles
- Treatment in carbon monoxide poisoning patients with headache: a prospective, multicenter, double-blind, controlled clinical trial. (Am J Emerg Med, 2016)
- [CO detector: a tool for the early diagnosis of carbon monoxide intoxication and a personal protective equipment. The experience of the Emergency Medical Sevice (118) in the Province of Cuneo]. (G Ital Med Lav Ergon, 2015)
- S2k guideline diagnosis and treatment of carbon monoxide poisoning. (Ger Med Sci, 2021)
- Characteristics of patients with carbon monoxide poisoning due to smoke inhalation and pre-hospital factors related to intensive care unit admission of these patients: a nationwide observational study (Signa Vitae, 2021)
- Carbon monoxide toxicity: audit on dysglycaemia link and guideline compliance (Journal of Paramedic Practice, 2026)
- [Experience with pulse carbon monoxide oximetry for prehospital assessment of patients exposed to smoke from fires in closed spaces in Catalonia]. (Emergencias, 2015)